Title



    mrrobust -- commands for two-sample Mendelian randomization (MR) analyses.



    https://remlapmot.github.io/mrrobust/



Commands



      mr            Primary command syntax, i.e. use mr egger ... syntax instead of mregger ...



      mrdeps        Install dependencies for the package



      mregger       MR-Egger and inverse-variance weighted (IVW) estimators



      mreggersimex  Simulation extrapolation algorithm for the MR-Egger model



      mreggerplot   Scatter plot showing instrument specific estimates with IVW, MR-Egger, or
                      median fitted line and confidence interval



      mrmedian      Unweighted, weighted, and penalized weighted median estimators for summary
                      level data



      mrmedianobs   Unweighted, weighted, and penalized weighted median estimators for individual
                      level data



      mrmodal       Modal estimator for summary level data



      mrmodalplot   Plot of density used in the modal estimator



      mrratio       Ratio (Wald) estimator for summary level data for a single genotype



      mrivests      Generate ratio (Wald) estimates for summary level data in dataset



      mrforest      Forest plot of genotype specific and model (IVW, MR-Egger, Median, Modal) IV
                      estimates



      mrfunnel      Funnel plot of the genotype specific IV estimates



      mrmvivw       Multivariable inverse variance weighted estimator (also mvivw and mvmr)



      mrmvegger     Multivariable MR-Egger regression



      mrleaveoneout Leave one out analysis



Description



    mrrobust is a suite of programs implementing recently developed estimators which are robust to
    certain proportions of invalid instrumental variables.



    Most of the commands are designed to use summary level data as provided by repositories such
    as MR-Base.



    The estimators were developed in the context of MR studies but could be used for other
    applications of instrumental variables.



    There is a website showing the examples from the helpfiles here: 
    https://remlapmot.github.io/mrrobust/



Author



INCLUDE help mrrobust-author