Title


ivmsmm -- Multiplicative structural mean model

Syntax

ivmsmm depvar [varlist1] (varlist2 = varlist_iv) [if] [in] [weight] [, log noirr ivpoisson_options]

varlist1 is the list of exogenous variables.

varlist2 is the list of endogenous variables.

varlist_iv is the list of exogenous variables used with varlist1 as instruments for varlist2.

options Description ---------------------------------------------------------------------------------------------- noirr Do not display exponentiated estimates log Show the GMM iteration log ivpoisson_options ivpoisson##optionstbl

Description

ivmsmm implements the multiplicative structural mean model (MSMM) of Robins (1989) as a wrapper to ivpoisson with the multiplicative option. ivpoisson performs generalized method of moments (GMM) estimation of the relevant moment condition using gmm.

The equivalence of the models of Robins (1989) and Mullahy (1997), which was implemented in ivpois, Nichols (2007) and ivpoisson with the mult option, and discussed in detail by Windmeijer and Santos Silva (1997) and Windmeijer (2002), was shown by Palmer (2011). These models produce moment conditions equivalent to gamma regression Dukes and Vansteelandt (2018).

Options

Please see ivpoisson##options

Examples

Read in binary outcome data; y outcome, x exposure, w covariate, z* instrumental variables (genotypes).

. use https://raw.github.com/remlapmot/ivonesamplemr/main/data/ivbinoutdata, clear

Fit the model with a single instrumental variable.

. ivmsmm y (x = z1)

Fit the model with multiple instruments.

. ivmsmm y (x = z1 z2 z3) . estat overid

Adjusting for w.

. ivmsmm y w (x = z1 z2 z3)

Fit the model with multiple exposures, and instruments, and adjusting for w.

. ivmsmm y w (x1 x2 = z1 z2 z3) . estat overid

Comparison with ivpois (specify onestep option to ivmsmm/ivpoisson for equivalence).

. ivpois y, endog(x) exog(z1) eform(RR) . ivpois y, endog(x) exog(z1 z2 z3) eform(RR) . ivpois y w, endog(x) exog(z1 z2 z3) eform(RR) . ivpois y w, endog(x1 x2) exog(z1 z2 z3) eform(RR)

Stored results

Please see ivpoisson##results

References

Cameron AC, Trivedi PK. Regression analysis of count data. 2nd ed. 2013. New York, Cambridge University Press.

Clarke PS, Palmer TM, Windmeijer F. Estimating structural mean models with multiple instrumental variables using the Generalised Method of Moments. Statistical Science, 2015, 30, 1, 96-117. DOI

Dukes O, Vansteelandt S. A note on G-estimation of causal risk ratios. American Journal of Epidemiology, 2018, 187, 5, 1079-1084. DOI

Hernán and Robins. Instruments for causal inference: An Epidemiologist's dream? Epidemiology, 2006, 17, 360-372. DOI

Mullahy J. Instrumental-variable estimation of count data models: applications to models of cigarette smoking and behavior. The Review of Economics and Statistics. 1997, 79, 4, 586-593. DOI

Nichols A. ivpois: Stata module for IV/GMM Poisson regression. 2007. URL

Palmer TM, Sterne JAC, Harbord RM, Lawlor DA, Sheehan NA, Meng S, Granell R, Davey Smith G, Didelez V. Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses. American Journal of Epidemiology, 2011, 173, 12, 1392-1403. DOI

Robins JM. The analysis of randomised and nonrandomised AIDS treatment trials using a new approach to causal inference in longitudinal studies. In Health Service Research Methodology: A Focus on AIDS (L. Sechrest, H. Freeman and A. Mulley, eds.). 1989. 113–159. US Public Health Service, National Center for Health Services Research, Washington, DC.

StataCorp. Stata Base Reference Manual. Release 13. ivpoisson - Poisson model with continuous endogenous covariates. 2013. URL

Windmeijer FAG, Santos Silva JMC. Endogeneity in Count Data Models: An Application to Demand for Health Care. Journal of Applied Econometrics. 1997, 12, 3, 281-294. DOI

Windmeijer, F. ExpEnd, A Gauss programme for non-linear GMM estimation of EXPonential models with ENDogenous regressors for cross section and panel data. CEMMAP working paper CWP14/02. 2002. URL

Author

INCLUDE help ivonesamplemr-author